Ketamine Clinics in Sioux Falls, SD
Browse 7 ketamine therapy providers in Sioux Falls, South Dakota.
Pax Institute
521 E Sandpiper Trl
Sioux Falls,
SD
57108
Pax Institute
521 E Sandpiper Trl
Sioux Falls,
SD
57108
Shannon Heard
317 N Main Ave STE 100
Sioux Falls,
SD
57104
Concordia Mind Health
5000 S Minnesota AVE Ste 201
Sioux Falls,
SD
57108
Clay Pavlis
4308 S Arway Dr
Sioux Falls,
SD
57106
Pax Institute
3803 W Technology Cir
Sioux Falls,
SD
57106
Britney Ohrlund
317 N Main Ave Ste 100
Sioux Falls,
SD
57104
Ketamine Treatments in Sioux Falls
Explore ketamine treatment options available in Sioux Falls, South Dakota.
IV Ketamine Infusion
Off-label psychiatric use. Verify protocols, evidence, risks, and pricing with the provider.
IM Injection
Off-label psychiatric use. Availability and clinical protocols vary by provider.
Spravato (Esketamine)
FDA-approved nasal spray administered in a REMS-certified healthcare setting.
Ketamine-Assisted Psychotherapy
Off-label and still under study. Evidence, training, and protocols vary.
About Ketamine Therapy in Sioux Falls, South Dakota
Sioux Falls has 7 ketamine therapy providers serving the South Dakota area. This includes 5 Spravato REMS-certified centers and 2 ASKP member clinics. Available treatments include IV ketamine infusion, FDA-approved Spravato (esketamine) nasal spray, and ketamine-assisted psychotherapy (KAP). These therapies target conditions including treatment-resistant depression, PTSD, anxiety, and chronic pain.
Spravato is FDA-approved and often covered by insurance with prior authorization — patients in Sioux Falls can check with the 5 certified centers listed above for coverage details. IV ketamine infusions typically cost $400–$800 per session for a standard 6-infusion protocol over 2–3 weeks. See our complete therapy guide for detailed information on treatment protocols, costs, and what to expect.
Contact clinics directly to verify current availability, accepted insurance, and scheduling. Additional providers may be available in nearby South Dakota cities listed below.